DNA Based Molecular Markers: A Tool for Differentiation of Ayurvedic Raw Drugs and their Adulterants

Pharmacognosy Reviews,2020,14,27,72-81.
Published:June 2020
Type:Review Article
Author(s) affiliations:

Manasi Malgaonkar1, Amey Shirolkar1, Soma Narasimha Murthy1, Anupam K Mangal2, Sharad Daulatrao Pawar1*

1Regional Ayurveda Institute of Fundamental Research, Under CCRAS; Min. of AYUSH, Nehru Garden, Gandhi Bhavan Road, Kothrud, Pune, Maharashtra, INDIA.

2Central Council for Research in Ayurvedic Sciences, Under Min. of AYUSH, Janakpuri, New Delhi, INDIA.


Recent advances in molecular techniques have generated several typing methods based on PCR for genetic assessment of genetic relatedness of plant species. Considering the medicinal importance of plants, it is essential to explore, discover and conserve genetic diversity of these plant species. Levels of polymorphisms represent genetic distance at intra-species level and method used to detect it is efficient marker for assessment of genetic relatedness. With this background, an attempt has been made to summarize the applicability of different DNA based molecular Markers for differentiation of Ayurvedic raw drugs and their adulterants considering the current practices and future perspectives.