Review Article
    Pharmacognosy Reviews
    Vol. 5
    Issue 10
    2011
    pp. 120-137
    Open Access

    Systematic review of herbals as potential anti-infl ammatory agents: Recent advances, current clinical status and future perspectives

    Sarwar Beg1,Suryakanta Swain2,Hameed Hasan3,M Abul Barkat3,Md Sarfaraz Hussain4
    1Department of Pharamaceutics, Faculty of Pharmacy, Jamia Hamdard, Hamdard Nagar, New Delhi.
    2Department of Pharmaceutics, Roland Institute of Pharmaceutical Sciences, Khodasingi, Berhampur, Orissa.
    3Department of Pharmacognosy, Faculty of Pharmacy, Jamia Hamdard, Hamdard Nagar, New Delhi.
    4Department of Pharmacognosy, Faculty of Pharmacy, Integral University, Khursi Road, Lucknow, INDIA.
    Correspondence:

    *Sarwar Beg

    Department of Pharamaceutics Faculty of Pharmacy, Jamia Hamdard, Hamdard Nagar, New Delhi.

    sarwar.beg@gamail.com

    Copyright:

    2011 Author(s)

    Check for updates
    Published:22/12/2011
    Received: 31/08/2010
    Accepted: 15/10/2011

    Abstract

    Many synthetic drugs reported to be used for the treatment of inflammatory disorders are of least interest now a days due to their potential side effects and serious adverse effects and as they are found to be highly unsafe for human assistance. Since the last few decades, herbal drugs have regained their popularity in treatment against several human ailments. Herbals containing anti-inflammatory activity (AIA) are topics of immense interest due to the absence of several problems in them, which are associated with synthetic preparations. The primary objective of this review is to provide a deep overview of the recently explored anti-inflammatory agents belonging to various classes of phytoconstituents like alkaloids, glycosides, terpenoids, steroids, polyphenolic compounds, and also the compounds isolated from plants of marine origin, algae and fungi. Also, it enlists a distended view on potential interactions between herbals and synthetic preparations, related adverse effects and clinical trials done on herbals for exploring their AIA. The basic aim of this review is to give updated knowledge regarding plants which will be valuable for the scientists working in the field of anti-inflammatory natural chemistry.

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    Keywords

    Alkaloids
    anti-inflammatory agents
    cannabinoids
    clinical trials
    glycosides
    herbals
    inflammation
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