Review Article
    Pharmacognosy Reviews
    Vol. 5
    Issue 10
    2011
    pp. 159-163
    Open Access

    Investigations on Piper betle grown in Sri Lanka

    Arambewela L. S. R.1,Arawwawala L. D. A. M.1,Kumaratunga K. G2,Dissanayake D. S1,Ratnasooriya W. D.3,Kumarasingha S. P.4
    1Industrial Technology Institute, Bauddhaloka Mawatha, Colombo 7.
    2Food Control Laboratory, Ministry of Health, Anuradhapura.
    3Department of Zoology, University of Colombo.
    4Colombo North Teaching Hospital, Ragama, Sri Lanka (currently at Royal Perth Hospital, Perth, Australia).
    Correspondence:

    *Arawwawala L. D. A. M.

    Industrial Technology Institute, Bauddhaloka Mawatha, Colombo 7.

    menukaarawwawala@yahoo.com

    Copyright:

    2011 Author(s)

    Check for updates
    Published:22/12/2011
    Received: 07/07/2010
    Accepted: 11/10/2011

    Abstract

    Piper betle is an economically important plant cultivated in Sri Lanka. Although more than 12 cultivars of betel are reported in Sri Lanka, very few scientific investigations have been carried out on them. Studies on the chemical constituents indicated that safrole is the major constituent, followed by chavibitol acetate, in the essential oil of common betel leaves of Sri Lanka. Investigations on the bioactivities of P. betle revealed the presence of antimicrobial, insecticidal, antioxidant, antinociceptive, antidiabetic and gastroprotective activities. In addition, P. betle was found to be safe in terms of hepatotoxicity, renotoxicity, hematotoxicity, gross morphology, weights of organs, stress or aversive behaviors in rats. The above fi ndings indicate the vast potential of P. betle yet to be harnessed for the benefit of mankind and the betel industry of Sri Lanka.

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    Keywords

    Anatomy
    bioactivities
    chemical constituents
    morphology
    Piper betle
    safety profile
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