Plant Review
    Pharmacognosy Reviews
    Vol. 12
    Issue 23
    2018
    pp. 115-119
    Open Access

    Neurologic Effects of Licorice: A Review

    Parsa Ravanfar1,Golnaz Namazi1,Afshin Borhani-Haghighi1,Shaghayegh Zafarmand1
    1Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, IRAN.
    Correspondence:

    *Afshin Borhani-Haghighi

    Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, IRAN.

    neuro.ab@gmail.com

    Copyright:

    2018 Author(s)

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    Published:23/05/2018

    Abstract

    Licorice (Glycyrrhiza glabra) is an herbal medicine with several pharmacologic properties in ancient traditional medicine. Studies have provided evidence on its clinical efficacy in variety of medical conditions. There are evidences implying the neuroprotective role of licorice extract and its pharmacologically active ingredients in acute and chronic neurodegenerative processes. In the present study, we made a thorough search on existing publications on neuroprotective effects of licorice both in molecular/cellular and human/animal in vivo studies. There is strong evidence on both molecular and functional animal/human levels that suggest licorice extract or its pharmacologically active ingredients assert neuroprotective effects in acute and chronic neurologic disorders including ischemic stroke, Alzheimer’s disease, and Parkinson’s disease. Licorice extract can be used safely in therapeutic doses for optimizing the treatment of a variety of neurodegenerative disorders as well as decreasing the extent of neural tissue damage and neurologic deficits after cerebrovascular accidents.

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    Keywords

    Licorice
    neurologic
    review
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