Review Article
    Pharmacognosy Reviews
    Vol. 11
    Issue 22
    2017
    pp. 136-140
    Open Access

    Potential Antitumor Effects of Pomegranates and Its Ingredients

    Arshad H. Rahmani1,Mohammed A. Alsahli1,Saleh A. Almatroodi1
    1Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, SAUDI ARABIA.
    Correspondence:

    *Arshad H. Rahmani

    Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, SAUDI ARABIA.

    rehmani.arshad@gmail.com

    Copyright:

    2017 Author(s)

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    Published:17/09/2017

    Abstract

    The treatment based on plant or plant derivatives is a promising strategy in the killing of cancers cells. Moreover, wide-ranging finding has established that medicinal plant and its ingredient modulate several cells signaling pathways or inhibiting the carcinogenesis process. In this vista, pomegranates fruits, seeds and peels illustrate cancer preventive role seems to be due to rich source of antioxidant and other valuable ingredients. Furthermore, antitumour activities of pomegranates have been evidences through the modulation of cell signaling pathways including transcription factor, apoptosis and angiogenesis. In this review article, anti-tumor activity of pomegranates and its components or its different type of extracts are described to understand the mechanism of action of pomegranates in cancer therapy.

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    Keywords

    Antioxidant
    anti‑tumor
    bioavailability
    cell signaling pathways
    pomegranates
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