Review Article
    Pharmacognosy Reviews
    Vol. 9
    Issue 17
    2015
    pp. 12-18
    Open Access

    Cucurbitacins – An insight into medicinal leads from nature

    Ujjwal Kaushik1,Vidhu Aeri1,Showkat R. Mir1
    1Department of Pharmacognosy and Phytochemistry, Phytochemistry Research Laboratory, Faculty of Pharmacy, New Delhi, INDIA.
    Correspondence:

    *Vidhu Aeri

    Department of Pharmacognosy and Phytochemistry, Phytochemistry Research Laboratory, Faculty of Pharmacy, New Delhi, INDIA.

    vidhuaeri@yahoo.com

    Copyright:

    2015 Author(s)

    Check for updates
    Published:28/05/2015
    Received: 05/03/2014
    Accepted: 05/05/2014

    Abstract

    Cucurbitacins which are structurally diverse triterpenes found in the members of Cucurbitaceae and several other plant families possess immense pharmacological potential. This diverse group of compounds may prove to be important lead molecules for future research. Research focused on these unattended medicinal leads from the nature can prove to be of immense significance in generating scientifically validated data with regard to their efficacy and possible role in various diseases. This review is aimed to provide an insight into the chemical nature and medicinal potential of these compounds exploring their proposed mode of action, probable molecular targets and to have an outlook on future directions of their use as medicinal agents.

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    Keywords

    Cucurbitaceae
    cucurbitacin
    triterpenoids
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