Review Article
    Pharmacognosy Reviews
    Vol. 6
    Issue 11
    2012
    pp. 29-36
    Open Access

    The chemotherapeutic potential of Terminalia ferdinandiana: Phytochemistry and bioactivity

    S. Mohanty1,Ian E. Cock1
    1Biomolecular and Physical Sciences, Environmental Future Centre, Nathan Campus, Griffith University, Nathan Brisbane, Queensland, AUSTRALIA.
    Correspondence:

    *Ian E. Cock

    Biomolecular and Physical Sciences, Environmental Future Centre, Nathan Campus, Griffith University, Nathan Brisbane, Queensland, AUSTRALIA.

    I.Cock@griffith.edu.au

    Copyright:

    2012 Author(s)

    Check for updates
    Published:23/05/2012
    Received: 25/03/2011
    Accepted: 04/04/2012

    Abstract

    Plants contain a myriad of natural compounds which exhibit important bioactive properties. These compounds may provide alternatives to current medications and afford a significant avenue for new drug discovery. Despite this, little information is available in the literature regarding native Australian plants and their potential for medicinal and industrial uses. Recent studies have reported Terminalia ferdinandiana to be an extremely good source of antioxidants. Indeed, T. ferdinandiana has been reported to have ascorbic acid levels per gram of fruit more than 900 times higher than blueberries. T. ferdinandiana also has high levels of a variety of other antioxidants, including phenolic compounds and anthocyanins. Antioxidants have been associated with the prevention of cancer, cardiovascular diseases, and neurological degenerative disorders. They are also linked with antidiabetic bioactivities and have been associated with the reduction of obesity. Antioxidants can directly scavenge free radicals, protecting cells against oxidative stress-related damage to proteins, lipids, and nucleic acids. Therefore, T. ferdinandiana has potential in the treatment of a variety of diseases and disorders and its potential bioactivities warrant further investigation.

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    Keywords

    Australian medicinal plants
    antioxidants
    gubinge
    Kakadu plum
    Terminalia ferdinandiana
    vitamin C
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