Review Article
    Pharmacognosy Reviews
    Vol. 20
    Issue 39
    2026
    pp. 54-62
    Open Access

    Targeting Tumor Growth and Progression in Carcinoma Prevention through Natural Catechol as Chemo Preventive Agents

    Siddhant Krishna1,Sandip Chatterjee2,Pawan Kumar Goswami3
    1Department of Pharmacology, Narayan Institute of Pharmacy, Gopal Narayan Singh University, Sasaram, Bihar, INDIA.
    2Department of Pharmacognosy, SRM Modinagar College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science and Technology, Delhi NCR campus, Ghaziabad, Uttar Pradesh, INDIA.
    3Department of Pharmaceutical Analysis, Narayan Institute of Pharmacy, Gopal Narayan Singh University, Sasaram, Bihar, INDIA.
    Correspondence:

    *Sandip Chatterjee

    Department of Pharmacognosy, SRM Modinagar College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science and Technology, Delhi NCR campus, Ghaziabad, Uttar Pradesh, INDIA.

    sandipkarna1994@gmail.com

    Copyright:

    2026 Author(s)

    Check for updates
    Published:11/03/2026
    Received: 03/12/2025
    Accepted: 24/02/2026

    Abstract

    Green tea is rich in catechins, which are polyphenolic chemicals that have strong anticancer effects through pro-apoptotic, anti-inflammatory, and antioxidant processes. They alter a number of molecular pathways, including as those that control the course of the cell cycle, limit angiogenesis, and reduce metastasis. With traditional Chemotherapeutics, Epigallocatechin Gallate (EGCG), the most researched catechin, exhibits synergistic actions that increase efficacy and decrease toxicity. Catechins may serve as both preventive and therapeutic agents in the treatment of carcinoma, according to data from in vitro, in vivo, and a small number of clinical investigations. However, issues like poor absorption and varying patient reactions call for sophisticated administration methods and extensive clinical testing.

    Share on Mobile

    Scan to access on mobile

    Keywords

    Angiogenesis
    Apoptosis
    Bioavailability
    Cancer prevention
    Cancer therapy
    Carcinoma
    Catechins
    Epigallocatechin gallate
    Green tea
    Metastasis.
    No content available

    Related Articles