Chromolaena odorata (Family: Asteraceae) synonyms as Eupatorium odoratum is a traditional medicinal plant that is widely used for its wound healing property. In particular, the several parts of this herb have been used to treat wounds, burns and skin infections. Furthermore, it has also been shown to possess anticancer, antidiabetic, anti-hepatotoxic, anti-inflammatory, antimicrobial and antioxidant properties. Its phytochemical components are alkaloids, flavonoids, flavanone, essential oils, phenolics, saponins, tannins and terpenoids. The other important constituents of this plant are Eupolin, chromomoric acid, quercetagetin and quercetin, all of which contribute to its remedial properties. Published information on the wound healing property of C. odorata was gathered by the use of different scientific websites such as Google Scholar, Science Direct, PubMed and Web of Knowledge to provide an up-to-date review showing its importance.