Plants remain a vital source of drugs and at present, much emphasis is given to nutraceuticals. Herbal medicines have been the basis of treatment and cure for various diseases and physiological conditions in the traditional methods practiced such as ayurveda and homeopathy. Litchi chinensis belongs to the Sapindaceae family and is well-known in the Indian traditional system for its traditional uses. The parts of the plant used are leaves, flowers, fruits, seed, pulp and pericarp. All parts of the plant are rich sources of phytochemicals––epicatechin; procyanidin A2 and procyanidin B2; leucocyanidin; cyanidin glycoside, malvidin glycoside and saponins; butylated hydroxytoluene; isolariciresinol; kaempferol; rutin; and stigmasterol. In the present review, we explore the lychee's description, traditional medicinal uses and phytoconstituents and investigate the pharmacological activities in various parts of the lychee to show its importance in ethanopharmacology. This is so that this review can serve as a ready-to-use material for further research on the plant.
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