Are Medicinal Plants the Future of Loa loa Treatment?

Pharmacognosy Reviews,2018,12,23,133-137.
Published:May 2018
Type:Short Review
Authors:
Author(s) affiliations:

Mengome Line Edwige, Mewono Ludovic1, Aboughe-Angone Sophie

Traditional Medicine and Pharmacopoeia, National Center for Scientific and Technological Research, Bp 12 141 Libreville, 1Research Group in Immunology, Applied Microbiology, Hygiene and Physiology, Superior teachers training College of Libreville, Gabon

Abstract:

Loa loa filarial worm affects humans living in rural areas, urban slums, or conflict zones. This parasite is responsible for neglected tropical diseases, endemic in rainforest areas of the West and Central African. L. loa has also been diagnosed among travelers and migrants. In areas that are co‑endemic of L. loa filarial with other filariasis such as onchocerciasis, lymphatic filariasis, or mansonelliasis, the treatment by diethylcarbamazine or ivermectin increases the risk of severe adverse effects. To remedy to this, it would be interesting to explore other tracks such medicinal plants. Nearly 80% of worldwide seed traditional practitioners are the first choice, and a large number of medicinal plants were claimed to possess antifilarial activities. This review relates about medicinal plants used to treat L. loa filarial disease.