An Update Review on the Anthelmintic Activity of Bitter gourd, Momordica charantia

Pharmacognosy Reviews,2017,11,21,31-34.
Published:April 2017
Type:Review Article
Authors:
Author(s) affiliations:

Sutthaya Poolperm1, Wannee Jiraungkoorskul2

1Mahidol University International College, Mahidol University, Nakhon Pathom 73170, Thailand

2Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand

Abstract:

Momordica charantia (Family: Cucurbitales), as known as bitter melon or gourd, is a daily consumption as food and traditional medicinal plant in Southeast Asia and Indo-China. It has been shown to possess anticancer, antidepressant, antidiabetic, anti-inflammatory, antimicrobial, antiobesity, antioxidant and antiulcer properties. Its common phytochemical components include alkaloids, charantin, flavonoids, glycosides, phenolics, tannins and terpenoids. This plant is rich in various saponins including momordicin, momordin, momordicoside, karavilagenin, karaviloside and kuguacin, all of which have been reported to contribute to its remedial properties including antibacterial, antifungal, antiviral and antiparasitic infections. Based on established literature on the anthelmintic activity of M. charantia and possible mode of action, this review article has attempted to compile M. charantia could be further explored for the development of potential anthelmintic drug.